Tom & Jerry's Greatest Chases was released in 2000, and contains 14 Tom & Jerry Cartoons, all from the first Hanna/Barbera/MGM era. They are listed as they appear in order on the DVD. Dates are taken from the DVD, and may contradict other sources.

  1. Yankee Doodle Mouse (1943)
  2. Solid Serenade (1945)
  3. Tee for Two (1944)
  4. Mouse in Manhattan (1945)
  5. Zoot Cat (1943)
  6. Dr. Jekyll and Mr. Mouse (1947)
  7. The Cat Concerto (1946)
  8. The Little Orphan (1948)
  9. Salt Water Tabby (1947)
  10. Kitty Foiled (1947)
  11. Johann Mouse (1952)
  12. Jerry's Diary (1949)
  13. Jerry and the Lion (1949)
  14. Mice Follies (1954)

This was the first Tom & Jerry classic cartoon DVD released, and also contains the most T&J cartoons on a single DVD to date (Whiskers Away has 10, and Hijinks and Shrieks and Paws for a Holiday have 7 each). The other feature on this DVD is "The Worry Song," excerpted from Anchors Aweigh the 1945 MGM feature movie with a Tom & Jerry sequence (featuring Gene Kelly dancing with Jerry, in a manner that Gene would reprise with Kermit the Frog on the Muppet Show, years later). Tom and Jerry would also appear in the movie Dangerous when Wet (this time 'swimming' with Esther Williams).